Systemic steroids are taken orally as a pill or in an intramuscular injection. Systemic steroids mimic the effects of hormones produced by the adrenal glands. They have anti-inflammatory and immunosuppressive properties.

Systemic steroids are generally only used as a short-term measure to try to stop the hair from falling rapidly. Long-term use is usually avoided as there can be serious side effects when taken for longer periods. 

Systemic steroids might be prescribed to patients with the following alopecia types:

alopecia areata (including totalis and universalis), lichen planopilaris (LPP).